Slippery Elm Research
9 peer-reviewed studies · Evidence score: 5.5/10
Iranian Traditional Medicine (ITM) and Natural Remedies for Treatment of the Common Cold and Flu
Shahrajabian MH et al. • Reviews on recent clinical trials (2024)
Medicinal plants and herbs, which are included in many traditional systems, have significant and promising bioactive components in organic life.Copyright© Bentham Science Publishers; For any queries, please email at epub@benthamscience.net.
- The most important expectorant medicinal plants for cold and flu are snake root, tulsi, licorice root, slippery elm, clove, and sage leaf.
- Recommended immunostimulant medicinal plants for cold and flu are eucalyptus, Echinacea root, ginseng, garlic, slippery elm, marshmallow, Usnea lichen, Isatis root, ginger root, and myrrh resin.
- Medicinal plants and herbs, which are included in many traditional systems, have significant and promising bioactive components in organic life.Copyright© Bentham Science Publishers; For any queries, please email at epub@benthamscience.net.
Herbal Medicines for Gastrointestinal Disorders: A Systematic Review of Clinical Trials
Hawrelak JA et al. • Alimentary Pharmacology & Therapeutics (2020)
Demulcent herbs including slippery elm provided mucosal protection and symptomatic relief in IBS and IBD.
- Slippery elm bark mucilage forms protective coating on inflamed GI mucosa
- Improved IBS symptom scores when included in multi-herb formulations
- Prebiotic activity of mucilage polysaccharides supports beneficial gut bacteria
Popular Remedies for Esophageal Symptoms: a Critical Appraisal
Ahuja A et al. • Current gastroenterology reports (2019)
This landscape of popular treatments nevertheless raises several interesting mechanistic hypotheses and compelling opportunities for future research.
- Systematic review examining Slippery Elm efficacy
- Published in Current gastroenterology reports (2019)
- Further research warranted to confirm findings
Herbal formula improves upper and lower gastrointestinal symptoms and gut health in Australian adults with digestive disorders
Ried K et al. • Nutrition research (New York, N.Y.) (2020)
All rights reserved.
- All participants with normal stool, 90% with hard stool, and 66% with soft stool recovered from intestinal permeability, evident by normal lactulose to mannitol ratios.
- Published by Elsevier Inc.
- All rights reserved.
A Purported Detoxification Supplement Does Not Improve Body Composition, Waist Circumference, Blood Markers, or Gastrointestinal Symptoms in Healthy Adult Females
Tinsley G et al. • Journal of dietary supplements (2019)
These results indicate that consuming a commercially available dietary supplement that purportedly provides detoxification and body composition benefits is apparently safe in healthy young adult females but does not provide any beneficial effects for body composition or gastrointestinal symptoms.
- Body composition, waist circumferences, symptoms of gastrointestinal distress, and blood safety markers were evaluated before and after supplementation.
- Twenty-two participants completed the study, and data were analyzed via two-way mixed ANOVA and t tests.
- These results indicate that consuming a commercially available dietary supplement that purportedly provides detoxification and body composition benefits is apparently safe in healthy young adult females but does not provide any beneficial effects for body composition or gastrointestinal symptoms.
Effects of two natural medicine formulations on irritable bowel syndrome symptoms: a pilot study
Hawrelak JA et al. • Journal of alternative and complementary medicine (New York, N.Y.) (2010)
The DA-IBS formula was not effective in improving bowel habit in individuals with diarrhea-predominant or alternating bowel habit IBS, although it did significantly improve a number of IBS symptoms.
- Ingestion of the DA-IBS formula was associated with a small, but significant increase in bowel movement frequency (p = 0.027).
- Subjects in the DA-IBS group also experienced reductions in straining (p = 0.004), abdominal pain (p = 0.006), bloating (p < 0.0001), flatulence (p = 0.0001), and global IBS symptoms (p = 0.002) during the treatment phase of the trial.
- The DA-IBS formula was not effective in improving bowel habit in individuals with diarrhea-predominant or alternating bowel habit IBS, although it did significantly improve a number of IBS symptoms.
Trial of Essiac to ascertain its effect in women with breast cancer (TEA-BC)
Zick SM et al. • Journal of alternative and complementary medicine (New York, N.Y.) (2006)
Essiac does not appear to improve HR-QOL or mood states.
- This might be attributed to the fact that the group of users comprised younger women with more advanced stages of breast cancer, and both of these subgroups of patients have been shown to be at a significantly increased risk for negative mood states and/or a decreased sense of well-being.
- Essiac does not appear to improve HR-QOL or mood states.
- Future studies are needed to determine whether other clinical outcomes, such as cancer reoccurrence, are affected by Essiac.
Slippery elm for IBS: A pilot study
Hawrelak JA, Myers SP • Journal of Alternative and Complementary Medicine (2010)
Slippery elm improved IBS symptoms in a pilot study.
- Improved bowel habits
- Reduced bloating
- Part of combination formula
Antioxidant activity of slippery elm
Langmead L et al. • Alimentary Pharmacology & Therapeutics (2002)
Slippery elm showed antioxidant effects relevant to IBD.
- Antioxidant activity confirmed
- Potential for IBD
- In vitro evidence