About SupStack
A passion project to make sense of the supplement world.
Why this exists
This started out of frustration. I spent way too many hours reading studies, cross-referencing claims, and trying to figure out which supplements were actually worth taking. Every site I found was either trying to sell me something or buried useful information under walls of SEO content.
So I built the tool I wished existed: a simple way to see what the research actually says, compare options, and make decisions without wading through marketing hype.
What started as a personal spreadsheet grew into something bigger. SupStack now covers 218 supplements backed by over 7,931 studies sourced from PubMed, each one cross-checked against the claims on the site. It's still a work in progress — but every update makes the data more accurate and the coverage more complete.
What you'll find here
Evidence ratings
Each supplement gets a score based on how strong the research is. Not opinions — actual studies you can check yourself.
Goal-based recommendations
Pick what you're trying to improve, and SupStack shows you what's most likely to help based on the evidence.
Side-by-side comparisons
Can't decide between two supplements? Compare them on dosage, timing, effects, and safety all in one place.
Safety information
Drug interactions, side effects, and who should avoid what. The stuff that's often buried in fine print elsewhere.
Your supplement stack
Save the supplements you're taking or considering. Get a shareable link to show friends, trainers, or doctors.
Personal experiments
Run N-of-1 experiments on yourself. Set a baseline, follow a protocol, do regular check-ins, and get a personal verdict on whether a supplement works for you.
Behind the data
Every supplement on SupStack goes through an automated validation pipeline that checks claims against real research. Here's what that looks like in practice:
7,931+
PubMed Studies
Sourced directly from PubMed with DOI links to originals
1,760+
Claims Validated
Dosages, safety ratings, and effects cross-checked against studies
460+
Drug Interactions
Documented with severity levels and clinical context
The validation pipeline catches inconsistencies automatically — like a safety rating that's too generous given what the studies actually found, or an evidence score that doesn't match the ratio of positive to negative findings. When issues are found, the content gets updated. Read more about how this works on the methodology page.
What makes this different
Nothing for sale
No products, no affiliate links, no sponsored content. Just information.
Sources you can check
Every rating links back to the research. Don't take SupStack's word for it — look at the studies yourself.
Honest about uncertainty
If the evidence is weak or mixed, SupStack says so. No point pretending something works when the research isn't there.
Continuously validated
Every supplement is cross-checked against its studies automatically. Safety ratings, evidence scores, and dosage claims all get audited — and corrected when the data says otherwise.
Quick disclaimer
SupStack is for informational purposes only — it's not medical advice. Always talk to a doctor before starting any supplement, especially if you have health conditions or take medications. What works in studies doesn't always work for everyone, and supplements aren't meant to replace proper medical care.
Ready to dig in?
Start with your goals or browse the full supplement library.